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Amylin: From Mode of Action to Future Clinical Potential in Diabetes and Obesity | Diabetes Therapy | Springer Nature Link
This involved several distinct phases, from initial cell culture and direct differentiation to functional assays and in vivo transplantation
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This genetic validation confirms the peptide's dependence on β3-AR signaling for chronic metabolic effects, providing researchers with confidence in pathway-specific studies and enabling investigation of receptor-dependent mechanisms in various experimental models
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