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Hernández, López-Sánchez, and Rendón-Ramírez (2016) CYP2E1 Oxidation of alcohol by cytochrome P450 pathways, especially CYP2E1 which is induced by alcohol, are secondary pathways to remove alcohol especially at high concentrations
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The effect of APOE genotypes on iPSC-derived astrocytes was also investigated, with the APOE ε4/ε4 astrocytes showing similar morphologies and expression of the same astrocyte markers and chemokines (with the addition of the upregulation of CCL4 and CCL5) to the PSEN1 M146L astrocytes (Jones et al., 2017)
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